It may also be used to treat anxiety disorders, obsessive compulsive disorder, panic attacks, post traumatic stress, and premenstrual dysphoric disorder (PMDD). Paxil CR belongs to a of drugs ed selective serotonin-reuptake inhibitors (SSRIs). Caution should be used in the elderly because paroxetine is the most sedating and anticholinergic of the selective serotonin reuptake inhibitors The elderly are prone to SSRI/SNRI-induced hyponatremia; monitor closely 65 years In children and young adults, risks must be wehed against the benefits of taking antidepressants Patients should be monitored closely for changes in behavior, clinical worsening, and suicidal tendencies; this should be done during the initial 1-2 months of therapy and dosage adjustments The patient’s family should communicate any abrupt changes in behavior to the healthcare provider Worsening behavior and suicidal tendencies that are not part of the presenting symptoms may require discontinuation of therapy This drug is not approved for use in pediatric patients Clinical worsening and suicidal ideation may occur despite medication in adolescents and young adults (18-24 years) Use caution in patients with bipolar disorder, seizure disorder, history of suicidal thought/behavior Risk of mydriasis; may trger angle closure attack in patients with angle closure glaucoma with anatomiy narrow angles without a patent iridectomy Conflicting evidence regarding use of SSRIs during pregnancy and increased risk of persistent pulmonary hypertension of the newborn (see Pregnancy) Risk of complications such as feeding difficulties, irritability, and respiratory problems reported in neonates exposed to SNRIs/SSRIs late in third trimester Risk of cardiovascular defects in infants whose mothers took drug during early pregnancy Withdraw gradually Use lower starting dose in renal impairment (Cr Cl Pregnancy category: D Teratogenic effects: Epidemiologic studies have shown that infants exposed to paroxetine in the first trimester of pregnancy have an increased risk of congenital malformations, particularly cardiovascular malformations Use late in the third trimester associated with complications in newborns and may require prolonged hospitalization, respiratory support, and tube feeding A study of nearly 28,000 women taking SSRIs confirmed 5 previously reported birth defercts associated with paroxetine, including heart defects, anencephaly, and abdominal wall defects (BMJ 2015; 351:h3190) Several SSRIs (eg, fluoxetine, fluvoxamine, paroxetine, sertraline) are metabolized by CYP2D6 CYP2D6 is involved in the metabolism of approximately 20% of drugs in clinical use, and it displays large individual-to-individual variability in activity due to genetic polymorphisms More than 80 CYP2D6 variant alleles have been identified; however, 4 of the most prevalent alleles, CYP2D6*3, *4, *5, and *6, account for 93-97% of CYP2D6 poor metabolizers (PMs) CYP2D6*4, the most common variant (~25% frequency in whites), causes a splicing defect; CYP2D6*3 (2.7% frequency) causes a frameshift mutation; and CYP3D6*5 (2.6%) is an entire deletion of the CYP2D6 gene; individuals homozygous for these alleles have no CYP2D6 activity The impact of CYP2D6 activity is further complicated in some SSRIs (eg, fluoxetine, fluvoxamine, paroxetine, sertraline) that in addition to being substrates for CYP2D6, are also known to moderately inhibit CYP2D6 activity The above information is provided for general informational and educational purposes only.
Paxil cr dosages
PAXIL CR should be administered as a single daily dose, usually in the morning, with or without food. Patients were dosed in a range of 25 mg to 62.5 mg/day in the clinical trials demonstrating the effectiveness of PAXIL CR in the treatment of major depressive disorder. Paxil CR is a prescription medication used to treat depression, panic disorder, social anxiety disorder, and Premenstrual Dysphoric Disorder.
Hi all, Just wondering, is there any 1 out there that has had a positive experience with Paxil CR. I was put on Paxil CR a few years ago and I thought it was a miracle drug. I have been taking Paxil CR 37.5mg for about 7 months.
Paxil cr dosages
Paxil cr dosages
It works by increasing the amount of serotonin in the brain, a natural substance that helps maintain mental balance and elevate mood. Common side effects of Paxil CR include nausea and weakness. Do not drive or operate heavy machinery until you know how Paxil CR. The recommended starting Paxil CR dosage for treating depression is 25 mg once daily.
Elderly, debilitated, severe hepatic or renal impairment: initially 12.5mg once daily; max 50mg/day. Concomitant pimozide, linezolid, IV methylene blue, thioridazine. Increased risk of suicidal thinking and behavior in children, adolescents, and young adults; monitor for clinical worsening or unusual changes. Monitor for serotonin syndrome or neuroleptic malnant syndrome-like sns and symptoms; discontinue if occurs. WHERE CAN I BUY THE CHEAPEST XENICAL ONLINE
Paxil cr dosages:
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